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Identification of TRIM25 as a Negative Regulator of Caspase-2 Expression Reveals a Novel Target for Sensitizing Colon Carcinoma Cells to Intrinsic Apoptosis

Colorectal cancer (CRC) is one of the most common cancers that is characterized by a high mortality due to the strong metastatic potential of the primary tumor and the high rate of therapy resistance. Hereby, evasion of apoptosis is the primary underlying cause of reduced sensitivity of tumor cells...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Nasrullah, Usman, Haeussler, Kristina, Biyanee, Abhiruchi, Wittig, Ilka, Pfeilschifter, Josef, Eberhardt, Wolfgang
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952940/
https://ncbi.nlm.nih.gov/pubmed/31842382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121622
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