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T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions

The spontaneous contractions of collecting lymphatic vessels provide an essential propulsive force to return lymph centrally. These contractions are driven by an intrinsic electrical pacemaker, working through an unknown underlying ionic mechanism that becomes compromised in some forms of lymphedema...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: To, Kim H. T., Gui, Peichun, Li, Min, Zawieja, Scott D., Castorena-Gonzalez, Jorge A., Davis, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952455/
https://ncbi.nlm.nih.gov/pubmed/31919478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56953-3
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