Carisbamate Blockade of T-type Voltage-Gated Calcium Channels

OBJECTIVES: Carisbamate (CRS) is a novel monocarbamate compound that possesses anti-seizure and neuroprotective properties. However, the mechanisms underlying these actions remain unclear. Here, we tested both direct and indirect effects of CRS on several cellular systems that regulate intracellular...

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Veröffentlicht in:Epilepsia
Hauptverfasser: Kim, Do Young, Zhang, Fang-Xiong, Nakanishi, Stan T., Mettler, Timothy, Cho, Ik-Hyun, Ahn, Younghee, Hiess, Florian, Chen, Lina, Sullivan, Patrick G., Wayne Chen, S. R., Zamponi, Gerald W., Rho, Jong M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386822/
https://ncbi.nlm.nih.gov/pubmed/28230232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13710
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