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Aberrant expression of S-SCAM causes the loss of GABAergic synapses in hippocampal neurons
The duplication and deletion mutations of the S-SCAM/MAGI-2 gene are associated with schizophrenia and infantile spasms, respectively. S-SCAM is a unique synaptic scaffolding protein that localizes to both excitatory and GABAergic synapses. However, consequences of aberrant S-SCAM expression on GABA...
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| Publicado no: | Sci Rep |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952429/ https://ncbi.nlm.nih.gov/pubmed/31919468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57053-y |
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