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Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the bacterial type IV secretion system. Delivered CagA then undergoes tyrosine phosphorylation at the Glu-Pro-...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Mol Immunol
Asıl Yazarlar: Takahashi-Kanemitsu, Atsushi, Knight, Christopher T., Hatakeyama, Masanori
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952403/
https://ncbi.nlm.nih.gov/pubmed/31804619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0339-5
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