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γ-AApeptides–based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide

The abnormal folding and aggregation of functional proteins into amyloid is a typical feature of many age-related diseases, including Type II diabetes. Growing evidence has revealed that the prevention of aggregate formation in culprit proteins could retard the progression of amyloid diseases. Human...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Bolarinwa, Olapeju, Li, Chunpu, Khadka, Nawal, Li, Qi, Wang, Yan, Pan, Jianjun, Cai, Jianfeng
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952368/
https://ncbi.nlm.nih.gov/pubmed/31919432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56500-0
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