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γ-AApeptides–based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide
The abnormal folding and aggregation of functional proteins into amyloid is a typical feature of many age-related diseases, including Type II diabetes. Growing evidence has revealed that the prevention of aggregate formation in culprit proteins could retard the progression of amyloid diseases. Human...
Uloženo v:
| Vydáno v: | Sci Rep |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952368/ https://ncbi.nlm.nih.gov/pubmed/31919432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56500-0 |
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