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Melanoma cell-derived exosomes in plasma of melanoma patients suppress functions of immune effector cells

Melanoma patients’ plasma contains exosomes produced by malignant and normal cells. Plasma exosomes were isolated and separated by immunocapture into two fractions: melanoma cell-derived exosomes (MTEX) and normal cell-derived exosomes (non-MTEX). Immunosuppressive effects of MTEX on primary human i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sharma, Priyanka, Diergaarde, Brenda, Ferrone, Soldano, Kirkwood, John M., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952363/
https://ncbi.nlm.nih.gov/pubmed/31919420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56542-4
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