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Melanoma cell-derived exosomes in plasma of melanoma patients suppress functions of immune effector cells

Melanoma patients’ plasma contains exosomes produced by malignant and normal cells. Plasma exosomes were isolated and separated by immunocapture into two fractions: melanoma cell-derived exosomes (MTEX) and normal cell-derived exosomes (non-MTEX). Immunosuppressive effects of MTEX on primary human i...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Sharma, Priyanka, Diergaarde, Brenda, Ferrone, Soldano, Kirkwood, John M., Whiteside, Theresa L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952363/
https://ncbi.nlm.nih.gov/pubmed/31919420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56542-4
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