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RedH and PigC Catalyze the Biosynthesis of Hybrubins via Phosphorylation of 4′-Methoxy-2,2′-Bipyrrole-5′-Carbaldehyde
Hybrubins are “unnatural” alkaloids with the same 4′-methoxy-2,2′-bipyrrole-5′-methine moiety found in prodiginines and a different ring derived from tetramic acids. Here, we demonstrated that RedH, a homologue of prodigiosin synthetase PigC, was responsible for the biosynthesis of hybrubins A and B...
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| 發表在: | Appl Environ Microbiol |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952227/ https://ncbi.nlm.nih.gov/pubmed/31704680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02331-19 |
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