Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription

Human papillomaviruses (HPV) are causative agents in 5% of all cancers, including the majority of anogenital and oropharyngeal cancers. Downregulation of innate immune genes (IIGs) by HPV to promote the viral life cycle is well documented; E6 and E7 are known repressors of these genes. More recently...

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Détails bibliographiques
Publié dans:mSphere
Auteurs principaux: James, Claire D., Fontan, Christian T., Otoa, Raymonde, Das, Dipon, Prabhakar, Apurva T., Wang, Xu, Bristol, Molly L., Morgan, Iain M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952203/
https://ncbi.nlm.nih.gov/pubmed/31915229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00828-19
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