Soluble AXL as a marker of disease progression and survival in melanoma

Receptor tyrosine kinase AXL is a one-pass transmembrane protein upregulated in cancers and associated with lower survival and therapy resistance. AXL can be cleaved by the A Disintegrin and Metalloproteinases (ADAM)10 and ADAM17, yielding a soluble version of the protein. Elevated soluble AXL (sAXL...

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Bibliographic Details
Published in:PLoS One
Main Authors: Flem-Karlsen, Karine, Nyakas, Marta, Farstad, Inger Nina, McFadden, Erin, Wernhoff, Patrik, Jacobsen, Kari Dolven, Flørenes, Vivi Ann, Mælandsmo, Gunhild Mari
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952099/
https://ncbi.nlm.nih.gov/pubmed/31917795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227187
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