hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma

In recent years, new treatment options for malignant melanoma patients have enhanced the overall survival for selected patients. Despite new hope, most melanoma patients still relapse with drug-resistant tumors or experience intrinsic resistance to the therapy. Therefore, novel treatment modalities...

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Библиографические подробности
Опубликовано в: :Cell Death Discov
Главные авторы: Fleten, Karianne G, Flørenes, Vivi Ann, Prasmickaite, Lina, Hill, Oliver, Sykora, Jaromir, Mælandsmo, Gunhild M, Engesæter, Birgit
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149582/
https://ncbi.nlm.nih.gov/pubmed/28028438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.81
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