The MicroRNA-92a/Sp1/MyoD Axis Regulates Hypoxic Stimulation of Myogenic Lineage Differentiation in Mouse Embryonic Stem Cells

Hypoxic microenvironments exist in developing embryonic tissues and determine stem cell fate. We previously demonstrated that hypoxic priming plays roles in lineage commitment of embryonic stem cells. In the present study, we found that hypoxia-primed embryoid bodies (Hyp-EBs) efficiently differenti...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Lee, Seo-Yeon, Yang, Jimin, Park, Jung Hwa, Shin, Hwa Kyoung, Kim, Woo Jean, Kim, Su-Yeon, Lee, Eun Ju, Hwang, Injoo, Lee, Choon-Soo, Lee, Jaewon, Kim, Hyo-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951826/
https://ncbi.nlm.nih.gov/pubmed/31606324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.08.014
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