The MicroRNA-92a/Sp1/MyoD Axis Regulates Hypoxic Stimulation of Myogenic Lineage Differentiation in Mouse Embryonic Stem Cells

Hypoxic microenvironments exist in developing embryonic tissues and determine stem cell fate. We previously demonstrated that hypoxic priming plays roles in lineage commitment of embryonic stem cells. In the present study, we found that hypoxia-primed embryoid bodies (Hyp-EBs) efficiently differenti...

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Veröffentlicht in:Mol Ther
Hauptverfasser: Lee, Seo-Yeon, Yang, Jimin, Park, Jung Hwa, Shin, Hwa Kyoung, Kim, Woo Jean, Kim, Su-Yeon, Lee, Eun Ju, Hwang, Injoo, Lee, Choon-Soo, Lee, Jaewon, Kim, Hyo-Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951826/
https://ncbi.nlm.nih.gov/pubmed/31606324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.08.014
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