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The History of Deferiprone (L1) and the Paradigm of the Complete Treatment of Iron Overload in Thalassaemia

Deferiprone (L1) was originally designed, synthesised and screened in vitro and in vivo in 1981 by Kontoghiorghes G. J. following his discovery of the novel alpha-ketohydroxypyridine class of iron chelators (1978–1981), which were intended for clinical use. The journey through the years for the trea...

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Detalhes bibliográficos
Publicado no:Mediterr J Hematol Infect Dis
Main Authors: Kontoghiorghes, George J., Kleanthous, Marios, Kontoghiorghe, Christina N.
Formato: Artigo
Idioma:Inglês
Publicado em: Università Cattolica del Sacro Cuore 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951358/
https://ncbi.nlm.nih.gov/pubmed/31934321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2020.011
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