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Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia syndromes

The prevalence rate of thalassemia, which is endemic in Southeast Asia, the Middle East, and the Mediterranean, exceeds 100,000 live births per year. There are many genetic variants in thalassemia with different pathological severity, ranging from a mild and asymptomatic anemia to life-threatening c...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kontoghiorghe, Christina N, Kontoghiorghes, George J
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745840/
https://ncbi.nlm.nih.gov/pubmed/26893541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S79458
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