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Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia syndromes

The prevalence rate of thalassemia, which is endemic in Southeast Asia, the Middle East, and the Mediterranean, exceeds 100,000 live births per year. There are many genetic variants in thalassemia with different pathological severity, ranging from a mild and asymptomatic anemia to life-threatening c...

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Publicado en:Drug Des Devel Ther
Autores principales: Kontoghiorghe, Christina N, Kontoghiorghes, George J
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745840/
https://ncbi.nlm.nih.gov/pubmed/26893541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S79458
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