Toxicity evaluation of 6-mercaptopurine-Chitosan nanoparticles in rats

BACKGROUND: The 6-mercaptopurine (6-MP) is an effective immunosuppressant and anti-cancer drug. However, the usage of 6-MP is limited due to its well-known side effects, such as myelotoxicity and hepato-renal toxicity. To curtail the potential toxic effects, we have used chitosan as a natural biodeg...

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Bibliografiske detaljer
Udgivet i:Saudi Pharm J
Main Authors: Govindappa, Prem Kumar, Joladarashi, Darukeshwara, Hallur, Raghavendra Lakshmana Shetty, Sanganal, Jagadeesh S., Phani, Ayyalasomayajula Ratna
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950973/
https://ncbi.nlm.nih.gov/pubmed/31933529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2019.11.018
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