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Toxicity evaluation of 6-mercaptopurine-Chitosan nanoparticles in rats
BACKGROUND: The 6-mercaptopurine (6-MP) is an effective immunosuppressant and anti-cancer drug. However, the usage of 6-MP is limited due to its well-known side effects, such as myelotoxicity and hepato-renal toxicity. To curtail the potential toxic effects, we have used chitosan as a natural biodeg...
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| Publié dans: | Saudi Pharm J |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6950973/ https://ncbi.nlm.nih.gov/pubmed/31933529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2019.11.018 |
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