Metformin alleviates muscle wasting post-thermal injury by increasing Pax7-positive muscle progenitor cells

BACKGROUND: Profound skeletal muscle wasting and weakness is common after severe burn and persists for years after injury contributing to morbidity and mortality of burn patients. Currently, no ideal treatment exists to inhibit muscle catabolism. Metformin is an anti-diabetic agent that manages hype...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Res Ther
Prif Awduron: Yousuf, Yusef, Datu, Andrea, Barnes, Ben, Amini-Nik, Saeid, Jeschke, Marc G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950874/
https://ncbi.nlm.nih.gov/pubmed/31915055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1480-x
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