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Metformin alleviates muscle wasting post-thermal injury by increasing Pax7-positive muscle progenitor cells

BACKGROUND: Profound skeletal muscle wasting and weakness is common after severe burn and persists for years after injury contributing to morbidity and mortality of burn patients. Currently, no ideal treatment exists to inhibit muscle catabolism. Metformin is an anti-diabetic agent that manages hype...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Yousuf, Yusef, Datu, Andrea, Barnes, Ben, Amini-Nik, Saeid, Jeschke, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950874/
https://ncbi.nlm.nih.gov/pubmed/31915055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1480-x
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