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Insights on the Conformational Ensemble of Cyt C Reveal a Compact State during Peroxidase Activity
Cytochrome c (cyt c) is known for its role in the electron transport chain but transitions to a peroxidase-active state upon exposure to oxidative species. The peroxidase activity ultimately results in the release of cyt c into the cytosol for the engagement of apoptosis. The accumulation of oxidati...
Gespeichert in:
Veröffentlicht in: | Biophys J |
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Hauptverfasser: | , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The Biophysical Society
2020
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6950772/ https://ncbi.nlm.nih.gov/pubmed/31810655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.011 |
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