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Insights on the Conformational Ensemble of Cyt C Reveal a Compact State during Peroxidase Activity

Cytochrome c (cyt c) is known for its role in the electron transport chain but transitions to a peroxidase-active state upon exposure to oxidative species. The peroxidase activity ultimately results in the release of cyt c into the cytosol for the engagement of apoptosis. The accumulation of oxidati...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Chea, Emily E., Deredge, Daniel J., Jones, Lisa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950772/
https://ncbi.nlm.nih.gov/pubmed/31810655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.011
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