Porcine Circovirus Type 2 Rep Enhances IL-10 Production in Macrophages via Activation of p38-MAPK Pathway

Porcine circovirus type 2 (PCV2) is one of the major threats to pig farms worldwide. Although PCV2 has been identified to promote IL-10 production, the detailed regulatory roles of PCV2 Rep for IL-10 production remain unclear. Herein, we first found that PCV2 Rep, rather than PCV1 Rep, enhanced IL-1...

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Veröffentlicht in:Viruses
Hauptverfasser: Wu, Xingchen, Wang, Xiaoya, Shi, Tengfei, Luo, Le, Qiao, Dan, Wang, Zhenyu, Han, Cong, Du, Qian, Tong, Dewen, Huang, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950681/
https://ncbi.nlm.nih.gov/pubmed/31835539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11121141
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