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Fucoxanthin Alleviates Oxidative Stress through Akt/Sirt1/FoxO3α Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs

As one of the main marine carotenoids, fucoxanthin has strong antioxidant activity. FoxO3α, a member of the forkhead box O family of transcription factors, plays an important role in DN by regulating oxidative stress. The activity of FoxO3α is related to its phosphorylation and acetylation status, r...

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Vydáno v:Mar Drugs
Hlavní autoři: Yang, Guanyu, Jin, Lin, Zheng, Dongxiao, Tang, Xiaoliang, Yang, Junwei, Fan, Lingxuan, Xie, Xi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950607/
https://ncbi.nlm.nih.gov/pubmed/31842414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17120702
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