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The expression of the nicotinic acetylcholine receptor α3 subunit in the brains of patients with Alzheimer’s disease and its effects on α- and γ-secretases and Notch signal transduction in SH-SY5Y cells

Objective: The aim of this study was to evaluate the correlation between the nicotinic acetylcholine receptor α3 subunit (α3nAChR) and β-amyloid (Aβ) in Alzheimer’s disease (AD) patients’ brains, α3nAChR on α and γ-secretases in amyloid precursor protein (APP) metabolism, and determine the possible...

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Dettagli Bibliografici
Pubblicato in:Int J Clin Exp Pathol
Autori principali: Ren, Jiamou, Wang, Xiaoling, Gao, Yumei, Wang, Fan, Guan, Zhizhong, Qi, Xiaolan
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949849/
https://ncbi.nlm.nih.gov/pubmed/31934215
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