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HCMV-encoded IE2 induces anxiety-depression and cognitive impairment in UL122 genetically-modified mice

Although there is a high risk of mood disorders and cognitive impairment in congenital human cytomegalovirus (HCMV) infections, the molecular pathogenetic mechanisms of HCMV have not yet been fully determined. In this study, we show that immediate-early 2 (IE2) protein modulates affective and cognit...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Mu, Haiyu, Wang, Zhifei, Zhang, Xianjuan, Qian, Dongmeng, Wang, Yuyang, Jiang, Shasha, Liang, Shuzhen, Wang, Bin
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949793/
https://ncbi.nlm.nih.gov/pubmed/31933804
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