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HCMV-encoded IE2 induces anxiety-depression and cognitive impairment in UL122 genetically-modified mice

Although there is a high risk of mood disorders and cognitive impairment in congenital human cytomegalovirus (HCMV) infections, the molecular pathogenetic mechanisms of HCMV have not yet been fully determined. In this study, we show that immediate-early 2 (IE2) protein modulates affective and cognit...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Mu, Haiyu, Wang, Zhifei, Zhang, Xianjuan, Qian, Dongmeng, Wang, Yuyang, Jiang, Shasha, Liang, Shuzhen, Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949793/
https://ncbi.nlm.nih.gov/pubmed/31933804
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