Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling

BACKGROUND: Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. This study demonstrates the antiangiogenic effects of scutellarin (SCU) on high glucose- and hypoxia-stimulated human retinal endothelial cells (HRECs) and on a diabetic rat model by oral administration. The a...

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Vydáno v:J Diabetes Res
Hlavní autoři: Long, Lingli, Li, Yubin, Yu, Shuang, Li, Xiang, Hu, Yue, Long, Tengfei, Wang, Liqin, Li, Wenwen, Ye, Xiaoxin, Ke, Zunfu, Xiao, Haipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949683/
https://ncbi.nlm.nih.gov/pubmed/31976335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4875421
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