Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling

BACKGROUND: Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. This study demonstrates the antiangiogenic effects of scutellarin (SCU) on high glucose- and hypoxia-stimulated human retinal endothelial cells (HRECs) and on a diabetic rat model by oral administration. The a...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Long, Lingli, Li, Yubin, Yu, Shuang, Li, Xiang, Hu, Yue, Long, Tengfei, Wang, Liqin, Li, Wenwen, Ye, Xiaoxin, Ke, Zunfu, Xiao, Haipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949683/
https://ncbi.nlm.nih.gov/pubmed/31976335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4875421
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