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PiggyBac-modified CD19-expressing 4T1 cell line for the evaluation of CAR construct

Reliable and stable target cell lines are required for evaluating the efficiency and studying the mechanism of chimeric antigen receptor T (CAR-T) immunotherapy both in vitro and in vivo. Jurkat cells can be used as an alternative for human primary lymphocytes to evaluate the constructs and function...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Hu, Han, Wang, Runyang, Zhang, Ziyi, Duan, Haixiao, Wang, Yang, Jin, Jing, Chen, Ying, Wu, Zhen, Fang, Zhizheng, Liu, Binlei
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949552/
https://ncbi.nlm.nih.gov/pubmed/31934091
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