Development of a novel anti-hepatitis B virus agent via Sp1

Nucleos(t)ide analog (NA) therapy has proven effective in treating chronic hepatitis B. However, NAs frequently result in viral relapse after the cessation of therapy. This is because NAs cannot fully eliminate the viral episomal covalently closed circular DNA (cccDNA) in the nucleus. In this study,...

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Publicado no:Sci Rep
Main Authors: Hayakawa, Michiyo, Umeyama, Hideaki, Iwadate, Mitsuo, Taguchi, Y.-H., Yano, Yoshihiko, Honda, Takashi, Itami-Matsumoto, Saori, Kozuka, Ritsuzo, Enomoto, Masaru, Tamori, Akihiro, Kawada, Norifumi, Murakami, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949255/
https://ncbi.nlm.nih.gov/pubmed/31913341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56842-9
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