Development of a novel anti-hepatitis B virus agent via Sp1

Nucleos(t)ide analog (NA) therapy has proven effective in treating chronic hepatitis B. However, NAs frequently result in viral relapse after the cessation of therapy. This is because NAs cannot fully eliminate the viral episomal covalently closed circular DNA (cccDNA) in the nucleus. In this study,...

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Pubblicato in:Sci Rep
Autori principali: Hayakawa, Michiyo, Umeyama, Hideaki, Iwadate, Mitsuo, Taguchi, Y.-H., Yano, Yoshihiko, Honda, Takashi, Itami-Matsumoto, Saori, Kozuka, Ritsuzo, Enomoto, Masaru, Tamori, Akihiro, Kawada, Norifumi, Murakami, Yoshiki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949255/
https://ncbi.nlm.nih.gov/pubmed/31913341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56842-9
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