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Fangchinoline protects against bone loss in OVX mice via inhibiting osteoclast formation, bone resorption and RANKL-induced signaling

Osteoporosis is a disease characterized by abnormally increased formation and function of osteoclasts. Anti-RANKL treatment using natural medicine is a potential therapy for osteoporosis. Here, we studied the effect of fangchinoline, which is extracted from the root of Stephania tetrandra S. Moore,...

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Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Zhou, Lin, Hong, Guoju, Li, Shangfu, Liu, Qian, Song, Fangming, Zhao, Jinmin, Yuan, Jinbo, Tickner, Jennifer, Xu, Jiake
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949157/
https://ncbi.nlm.nih.gov/pubmed/31929758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.37162
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