Disordered chromatin packing regulates phenotypic plasticity

Three-dimensional supranucleosomal chromatin packing plays a profound role in modulating gene expression by regulating transcription reactions through mechanisms such as gene accessibility, binding affinities, and molecular diffusion. Here, we use a computational model that integrates disordered chr...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Virk, Ranya K. A., Wu, Wenli, Almassalha, Luay M., Bauer, Greta M., Li, Yue, VanDerway, David, Frederick, Jane, Zhang, Di, Eshein, Adam, Roy, Hemant K., Szleifer, Igal, Backman, Vadim
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949045/
https://ncbi.nlm.nih.gov/pubmed/31934628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax6232
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