Human cells adapt to translational errors by modulating protein synthesis rate and protein turnover

Deregulation of tRNAs, aminoacyl-tRNA synthetases (aaRS) or tRNA modifying enzymes, increase the level of protein synthesis errors (PSE) and are associated with several diseases, but the cause-effect mechanisms of these pathologies remain elusive. To clarify the role of PSE in human biology, we have...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Varanda, Ana Sofia, Santos, Mafalda, Soares, Ana R., Vitorino, Rui, Oliveira, Patrícia, Oliveira, Carla, Santos, Manuel A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948982/
https://ncbi.nlm.nih.gov/pubmed/31570039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1670039
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