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Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates

Although protein synthesis dynamics has been studied both with theoretical models and by profiling ribosome footprints, the determinants of ribosome flux along open reading frames (ORFs) are not fully understood. Combining measurements of protein synthesis rate with ribosome footprinting data, we he...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Riba, Andrea, Di Nanni, Noemi, Mittal, Nitish, Arhné, Erik, Schmidt, Alexander, Zavolan, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660795/
https://ncbi.nlm.nih.gov/pubmed/31292258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817299116
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