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Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis
Glomerular disease is characterized by proteinuria and glomerulosclerosis, two pathologic features caused by podocyte injury and mesangial cell activation, respectively. However, whether these two events are linked remains elusive. Here, we report that sonic hedgehog (Shh) is the mediator that conne...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6948867/ https://ncbi.nlm.nih.gov/pubmed/31647783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130515 |
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