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Rapamycin-resistant effector T-cell therapy

Pharmacologic inhibition of the mechanistic target of rapamycin (mTOR) represents a stress test for tumor cells and T cells. Mechanisms exist that allow cells to survive this stress, including sub-optimal target block, alternative signaling pathways, and autophagy. Rapamycin-resistant effector T (T-...

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Bibliografiske detaljer
Udgivet i:Immunol Rev
Hovedforfatter: Fowler, Daniel H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948844/
https://ncbi.nlm.nih.gov/pubmed/24329799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12127
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