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Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs

Long noncoding RNA (lncRNA) transcripts have emerging impacts in cancer studies, which suggests their potential as novel therapeutic agents. However, the molecular mechanism behind their treatment effects is still unclear. Here, we designed a computational model to Associate LncRNAs with Anti-Cancer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Wang, Yongcui, Chen, Shilong, Chen, Luonan, Wang, Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948815/
https://ncbi.nlm.nih.gov/pubmed/31877126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007540
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