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Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs

Long noncoding RNA (lncRNA) transcripts have emerging impacts in cancer studies, which suggests their potential as novel therapeutic agents. However, the molecular mechanism behind their treatment effects is still unclear. Here, we designed a computational model to Associate LncRNAs with Anti-Cancer...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Wang, Yongcui, Chen, Shilong, Chen, Luonan, Wang, Yong
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948815/
https://ncbi.nlm.nih.gov/pubmed/31877126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007540
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