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Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs

Long noncoding RNA (lncRNA) transcripts have emerging impacts in cancer studies, which suggests their potential as novel therapeutic agents. However, the molecular mechanism behind their treatment effects is still unclear. Here, we designed a computational model to Associate LncRNAs with Anti-Cancer...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Wang, Yongcui, Chen, Shilong, Chen, Luonan, Wang, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948815/
https://ncbi.nlm.nih.gov/pubmed/31877126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007540
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