Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer

A 4-oxalocrotonate tautomerase (4-OT) trimer has been isolated from Burkholderia lata and a kinetic, mechanistic, and structural analysis has been performed. The enzyme is the third described oligomer state for 4-OT along with a homo- and heterohexamer. The 4-OT trimer is part of a small subset of s...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Baas, Bert-Jan, Medellin, Brenda P., LeVieux, Jake A., de Ruijter, Marieke, Zhang, Yan Jessie, Brown, Shoshana D., Akiva, Eyal, Babbitt, Patricia C., Whitman, Christian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948721/
https://ncbi.nlm.nih.gov/pubmed/31074977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00303
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