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MicroRNA-106a-3p Induces Apatinib Resistance and Activates Janus-Activated Kinase 2 (JAK2)/Signal Transducer and Activator of Transcription 3 (STAT3) by Targeting the SOCS System in Gastric Cancer

BACKGROUND: MicroRNA (miR)-106a was involved in the tumorigenesis and highly expressed in gastric cancer. Required apatinib resistance greatly limits its efficacy in patients. Thus, the aim of the present study was to investigate the potential role of miR-106a-3p in gastric cancer cells with apatini...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Med Sci Monit
Main Authors: Guo, Wei, Li, Wenyuan, Yuan, Li, Mei, Xianghuang, Hu, Wenqing
פורמט: Artigo
שפה:Inglês
יצא לאור: International Scientific Literature, Inc. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948289/
https://ncbi.nlm.nih.gov/pubmed/31884511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.919610
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