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MicroRNA-106a-3p Induces Apatinib Resistance and Activates Janus-Activated Kinase 2 (JAK2)/Signal Transducer and Activator of Transcription 3 (STAT3) by Targeting the SOCS System in Gastric Cancer

BACKGROUND: MicroRNA (miR)-106a was involved in the tumorigenesis and highly expressed in gastric cancer. Required apatinib resistance greatly limits its efficacy in patients. Thus, the aim of the present study was to investigate the potential role of miR-106a-3p in gastric cancer cells with apatini...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Med Sci Monit
Egile Nagusiak: Guo, Wei, Li, Wenyuan, Yuan, Li, Mei, Xianghuang, Hu, Wenqing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Scientific Literature, Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948289/
https://ncbi.nlm.nih.gov/pubmed/31884511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.919610
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