Preventive CTLA-4-Ig Treatment Reduces Hepatic Egg Load and Hepatic Fibrosis in Schistosoma mansoni-Infected Mice

BACKGROUND: Hepatic fibrosis and granuloma formation as a consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma mansoni infection. We have previously shown that single-sex infection with female schistosomes mitigates hepatic fibrosis after sec...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Sombetzki, Martina, Rabes, Anne, Bischofsberger, Miriam, Winkelmann, Franziska, Koslowski, Nicole, Schulz, Cindy, Reisinger, Emil C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948272/
https://ncbi.nlm.nih.gov/pubmed/31950032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1704238
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