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Preventive CTLA-4-Ig Treatment Reduces Hepatic Egg Load and Hepatic Fibrosis in Schistosoma mansoni-Infected Mice

Background. Hepatic fibrosis and granuloma formation as a consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma mansoni infection. We have previously shown that single-sex infection with female schistosomes mitigates hepatic fibrosis after sec...

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Hauptverfasser: Martina Sombetzki, Anne Rabes, Miriam Bischofsberger, Franziska Winkelmann, Nicole Koslowski, Cindy Schulz, Emil C. Reisinger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Limited 2019-01-01
Schriftenreihe:BioMed Research International
Online Zugang:http://dx.doi.org/10.1155/2019/1704238
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