Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy

The presence of disseminated tumour cells (DTCs) in BM predicts poorer metastasis-free survival of breast cancer patients with localized disease. DTCs persist in distant tissues despite systemic administration of adjuvant chemotherapy. Many assume this is because the majority of DTCs are quiescent....

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Bibliografski detalji
Izdano u:Nat Cell Biol
Glavni autori: Carlson, Patrick, Dasgupta, Arko, Grzelak, Candice A., Kim, Jeanna, Barrett, Alexander, Coleman, Ilsa M., Shor, Ryann E., Goddard, Erica T., Dai, Jinxiang, Schweitzer, Emma M., Lim, Andrea R., Crist, Sarah B., Cheresh, David A., Nelson, Peter S., Hansen, Kirk C., Ghajar, Cyrus M.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948102/
https://ncbi.nlm.nih.gov/pubmed/30664790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0267-0
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