Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

Gene therapy provides an ideal potential treatment for intervertebral disk degeneration by delivering synthetic microRNAs (miRNAs) to regulate the gene expression levels. However, it is very challenging to deliver miRNAs directly, which leads to inactivation, low transfection efficiency, and short h...

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Bibliografiske detaljer
Udgivet i:	Adv Sci (Weinh)
Main Authors:	Chen, Wei, Chen, Hao, Zheng, Dandan, Zhang, Hongbo, Deng, Lianfu, Cui, Wenguo, Zhang, Yuhui, Santos, Hélder A., Shen, Hongxing
Format:	Artigo
Sprog:	Inglês
Udgivet:	John Wiley and Sons Inc. 2019
Fag:	Full Papers
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6947697/ https://ncbi.nlm.nih.gov/pubmed/31921568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201902099
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Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

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