Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

Gene therapy provides an ideal potential treatment for intervertebral disk degeneration by delivering synthetic microRNAs (miRNAs) to regulate the gene expression levels. However, it is very challenging to deliver miRNAs directly, which leads to inactivation, low transfection efficiency, and short h...

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Detaylı Bibliyografya
Yayımlandı:Adv Sci (Weinh)
Asıl Yazarlar: Chen, Wei, Chen, Hao, Zheng, Dandan, Zhang, Hongbo, Deng, Lianfu, Cui, Wenguo, Zhang, Yuhui, Santos, Hélder A., Shen, Hongxing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Full Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947697/
https://ncbi.nlm.nih.gov/pubmed/31921568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201902099
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