Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

Gene therapy provides an ideal potential treatment for intervertebral disk degeneration by delivering synthetic microRNAs (miRNAs) to regulate the gene expression levels. However, it is very challenging to deliver miRNAs directly, which leads to inactivation, low transfection efficiency, and short h...

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Dades bibliogràfiques
Publicat a:Adv Sci (Weinh)
Autors principals: Chen, Wei, Chen, Hao, Zheng, Dandan, Zhang, Hongbo, Deng, Lianfu, Cui, Wenguo, Zhang, Yuhui, Santos, Hélder A., Shen, Hongxing
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947697/
https://ncbi.nlm.nih.gov/pubmed/31921568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201902099
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