Frequency and Clinical Outcomes of CYP2C19 Genotype-Guided Escalation and De-escalation of Antiplatelet Therapy in a Real-World Clinical Setting

PURPOSE: To evaluate the frequency and clinical impact of switches in antiplatelet therapy following implementation of CYP2C19 genotyping after percutaneous coronary intervention (PCI). METHODS: The frequency of escalation (clopidogrel switched to prasugrel/ticagrelor) and de-escalation (prasugrel/t...

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Publicado en:Genet Med
Main Authors: Martin, Jesse, Williams, Alexis K., Klein, Melissa D., Sriramoju, Vindhya B., Madan, Shivanshu, Rossi, Joseph S., Clarke, Megan, Cicci, Jonathan D., Cavallari, Larisa H., Weck, Karen E., Stouffer, George A., Lee, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946839/
https://ncbi.nlm.nih.gov/pubmed/31316169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41436-019-0611-1
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