Clinical Outcomes and Sustainability of Using CYP2C19 Genotype-guided Antiplatelet Therapy after Percutaneous Coronary Intervention

BACKGROUND: CYP2C19 loss-of-function (LOF) alleles impair clopidogrel effectiveness after percutaneous coronary intervention (PCI). The feasibility, sustainability and clinical impact of using CYP2C19 genotype-guided dual antiplatelet therapy (DAPT) selection in practice remains unclear. METHODS AND...

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Detalhes bibliográficos
Publicado no:Circ Genom Precis Med
Main Authors: Lee, Craig R., Sriramoju, Vindhya B., Cervantes, Alexandra, Howell, Lucius A., Varunok, Nicholas, Madan, Shivanshu, Hamrick, Kasey, Polasek, Melissa J., Lee, John Andrew, Clarke, Megan, Cicci, Jonathan D., Weck, Karen E., Stouffer, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889089/
https://ncbi.nlm.nih.gov/pubmed/29615454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.002069
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